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November 1, 1970Arthritis & Rheumatism

Oxygen tension in synovial fluids

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Authors

KLKnud Lund‐OlesenOdense University Hospital

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Implication

Cross-sectional analysis demonstrates severe hypoxia in synovial fluid from patients with rheumatoid arthritis, suggesting profound metabolic impairment in inflamed joints.

Key Points

  • To evaluate oxygen tension (pO2), carbon dioxide tension (pCO2), and pH in synovial fluid across different pathological knee conditions.
  • Analyzed 103 synovial fluid samples aspirated from knee joints of patients presenting with rheumatoid arthritis, osteoarthrosis, or traumatic joint exudates.
  • Measured oxygen tension (pO2), carbon dioxide tension (pCO2), and pH across all collected fluid specimens.
  • Synovial fluid pO2 was markedly reduced in rheumatoid arthritis compared to osteoarthrosis and traumatic joint exudates, dropping as low as 0 mmHg in some rheumatoid cases.
  • Synovial fluid oxygen tension showed statistically significant correlations with both pH and pCO2 across the evaluated samples.

Cite This Study

Knud Lund‐Olesen (1970) studied this question.

synapsesocial.com/papers/69f1ea62007b5feb1875c3eahttps://doi.org/10.1002/art.1780130606
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Some Features of Angiographic Findings in Rheumatoid Arthritis and Scleroderma1964 · 11 citations
  2. 2Arteriographic appearances in rheumatoid arthritis and other disorders1963 · 35 citations