Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based Sample
Why the study?
Is pericardial fat associated with cardiovascular disease risk factors and vascular calcification independently of visceral abdominal fat?
Population
1155 participants free of cardiovascular disease from the Framingham Heart Study, mean age 63 years, 54.8%…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Association warrants no practice change; leaves open causal role and incremental prognostic value in prospective studies.
Structured PICO
Is pericardial fat associated with cardiovascular disease risk factors and vascular calcification independently of visceral abdominal fat?
P
Population
1155 participants free of cardiovascular disease from the Framingham Heart Study, mean age 63 years, 54.8% women.
O
Outcome
Associations between intrathoracic and pericardial fat volumes and metabolic risk factors, coronary artery calcification, and abdominal aortic calcificationsurrogate
Pericardial fat is associated with coronary artery calcification independent of visceral abdominal fat, suggesting a potential local toxic effect of this fat depot on the coronary vasculature.
Cite This Study
Rosito et al. (2008) studied this question.