Why the study?
Sex-specific clinical data remain inadequate and molecular mechanisms linking psychological stress to ischemic heart disease in women remain elusive, particularly in postmenopausal women.
Does chronic psychological stress contribute to the pathogenesis of ischemic heart disease in women?
Population
Women with or at risk for ischemic heart disease, particularly postmenopausal women
Design
Review
Authors
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Stress effects on female IHD lack mechanistic clarity; leaves open targeted preclinical research before any practice implications.
Does chronic psychological stress contribute to the pathogenesis of ischemic heart disease in women?
Further preclinical research on female models is essential to elucidate the impact of stress on female cardiac health and develop targeted interventions for ischemic heart disease.
Cairns et al. (2025) studied this question.
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