Why the study?
Does intravenous immune globulin improve left ventricular ejection fraction in adults with recent-onset dilated cardiomyopathy or myocarditis?
Population
62 adults with recent onset of idiopathic dilated cardiomyopathy or myocarditis and LVEF ≤0.40. Mean age…
Comparison
Intravenous immune globulin (IVIG) 2 g/kg vs Placebo
Design
RCT, randomized, placebo-controlled
Follow-up
12 months
Authors
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IVIG should not be used to augment LVEF recovery in recent-onset cardiomyopathy; confirms no benefit over placebo in this population.
Does intravenous immune globulin improve left ventricular ejection fraction in adults with recent-onset dilated cardiomyopathy or myocarditis?
Intravenous immune globulin does not augment the improvement in left ventricular ejection fraction in patients with recent-onset dilated cardiomyopathy, though overall LVEF improves significantly over time.
McNamara et al. (2001) studied this question.
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