Why the study?
Are elevated soluble interleukin-2 receptor (sIL-2R) levels associated with disease severity and immune activation in patients with dilated cardiomyopathy?
Population
102 subjects total: 50 patients with idiopathic dilated cardiomyopathy, 30 patients with ischemic heart…
Design
Cross-sectional
Authors
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Supports T-cell activation research in dilated cardiomyopathy; hypothesis-generating and should not yet alter clinical management.
Are elevated soluble interleukin-2 receptor (sIL-2R) levels associated with disease severity and immune activation in patients with dilated cardiomyopathy?
Elevated sIL-2R levels, reflecting T-lymphocyte activation, are frequent in dilated cardiomyopathy and correlate with worse hemodynamic severity and higher autoantibody titers.
Limas et al. (1995) studied this question.
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