What question did this study set out to answer?

This study aims to evaluate the incidence of atrial fibrillation after surgical ablation of accessory pathways in Wolff-Parkinson-White syndrome patients.

July 1, 1985Circulation

Atrial fibrillation in patients with Wolff-Parkinson-White syndrome: incidence after surgical ablation of the accessory pathway.

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Why the study?

What are the electrophysiologic differences between Wolff-Parkinson-White syndrome patients with and without a history of atrial fibrillation?

Population

38 patients with Wolff-Parkinson-White syndrome undergoing surgical ablation of atrioventricular accessory…

Comparison

Preoperative electrophysiologic testing and… vs Patients with a history of only reciprocating…

Design

Cohort

Authors

ASArjun D. SharmaSutter Health GKGeorge J. KleinElectrophysiology GGG GuiraudonElectrophysiology

Discussion

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Implication

Shorter pathway refractoriness may flag higher-risk WPW patients; leaves open whether it predicts spontaneous AF or guides ablation.

Key Points

This study aims to evaluate the incidence of atrial fibrillation after surgical ablation of accessory pathways in Wolff-Parkinson-White syndrome patients.
Analyzed 50 consecutive surgical cases of patients with Wolff-Parkinson-White syndrome.
Compared 19 patients with atrial fibrillation history to 19 with only reciprocating tachycardia during the same timeframe.
Preoperative electrophysiologic testing was performed to identify factors indicative of atrial fibrillation.
Patients with a history of atrial fibrillation had a significantly shorter antegrade accessory pathway effective refractory period (270 ms vs 330 ms, p<0.05).
Induced atrial fibrillation showed faster ventricular rates in atrial fibrillation patients with an average RR interval of 324 ms vs 405 ms in those with only reciprocating tachycardia (p<0.01).
Electrophysiologic testing discovered that 18 of 19 patients with atrial fibrillation had induced episodes, with sustained arrhythmia in 14, while none sustained in the reciprocating tachycardia group.

Structured PICO

What are the electrophysiologic differences between Wolff-Parkinson-White syndrome patients with and without a history of atrial fibrillation?

Population

38 patients with Wolff-Parkinson-White syndrome undergoing surgical ablation of atrioventricular accessory pathways, including 19 with a history of spontaneous atrial fibrillation and 19 with a history of only reciprocating tachycardia.

Intervention

Preoperative electrophysiologic testing and surgical ablation of atrioventricular accessory pathways

Comparator

Patients with a history of only reciprocating tachycardia

Outcome

Electrophysiologic properties including antegrade accessory pathway effective refractory period and ventricular rates during induced atrial fibrillationsurrogate

Cite This Study

Sharma et al. (1985) studied this question.

synapsesocial.com/papers/69f29d081b51e2fbf018738c https://doi.org/10.1161/01.cir.72.1.161

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes Anticoagulation in AF

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Atrial fibrillation in patients with Wolff-Parkinson-White syndrome: incidence after surgical ablation of the accessory pathway.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Atrial fibrillation in patients with Wolff-Parkinson-White syndrome: incidence after surgical ablation of the accessory pathway.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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