Why the study?
Does increased aortic stiffness explain the higher cardiovascular mortality in diabetic patients with end-stage renal disease?
Population
265 end-stage renal disease (ESRD) patients on hemodialysis, including 50 diabetic patients
Comparison
Diabetes mellitus and increased aortic stiffness vs No diabetes mellitus and lower aortic stiffness
Design
Cohort
Follow-up
mean 63 months
Authors
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Aortic stiffness may mediate diabetes-related CV mortality in ESRD; hypothesis-generating for PWV-targeted interventions in prospective studies.
Does increased aortic stiffness explain the higher cardiovascular mortality in diabetic patients with end-stage renal disease?
Increased aortic stiffness in ESRD patients with diabetes mellitus is a key driver of their higher all-cause and cardiovascular mortality rates.
Shoji et al. (2001) studied this question.
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