Why the study?
What is the mechanism of left atrial enlargement in patients with hypertensive heart disease?
Population
15 subjects undergoing cardiac catheterization, comprising 7 patients with hypertensive heart disease and 8…
Comparison
Measurement of left atrial and left ventricular… vs Control subjects without hypertensive heart…
Design
Case-control
Authors
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Supports LA enlargement as diastolic marker in hypertension; hypothesis-generating for causality, needs prospective validation.
What is the mechanism of left atrial enlargement in patients with hypertensive heart disease?
Left atrial enlargement in hypertensive heart disease is associated with impaired left ventricular diastolic filling and increased LV stiffness.
Matsuda et al. (1996) studied this question.
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