A UV spectrophotometric method accurately measures nebivolol in bulk and tablets, highlighting method validation.
A simple, sensitive and accurate UV spectrophotometric method was developed for the assay of nebivolol hydrochloride in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 282 nm for nebivolol hydrochloride tablet solution. The linearity range was found to be 5–50 μg/mL for the drug. It was found that the excipients present in the commercial formulation did not interfere with the method.
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Kamila et al. (2007) studied this question.
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