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April 30, 2026Journal of Clinical MedicineOpen Access

The Relationship Between Early-Stage Maladaptive Schemas and Treatment Adherence in Patients Diagnosed with Bipolar Disorder in Remission

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Authors

MKMahmut Onur KaraytuğCukurova UniversityLTLut TamamCukurova UniversityMDMehmet Emin DemirkolCukurova University

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Implication

Cross-sectional study links cognitive vulnerability to treatment adherence in bipolar disorder, suggesting interventions target schemas.

Key Points

  • This research examines the link between early-stage maladaptive schemas and treatment adherence in bipolar disorder patients in remission.
  • Cross-sectional study design involving 156 euthymic patients with bipolar disorder
  • Assessment included Young Schema Questionnaire–Short Form 3 and Morisky Medication Adherence Scale
  • ANOVA and chi-square tests were conducted for group differences and ordinal logistic regression was used for factors associated with adherence.
  • Punishment schema showed the largest effect size on adherence
  • Higher Punishment schema scores were linked to poorer treatment adherence (OR = 1.14, p < 0.001)
  • Younger age and partial insight also correlated with lower adherence.

Cite This Study

Karaytuğ et al. (2026) studied this question.

synapsesocial.com/papers/69f2a47b8c0f03fd677638b2https://doi.org/10.3390/jcm15093351
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence1986 · 5,387 citations
  2. 2Insight and Psychosis1990 · 1,164 citations
  3. 3Nonadherence With Mood Stabilizers2002 · 318 citations
  4. 4Is there a universal need for positive self-regard?1999 · 2,143 citations
  5. 5Suicidal risk in bipolar I disorder patients and adherence to long‐term lithium treatment2006 · 192 citations