Case report reveals advanced gastric carcinoma after biliopancreatic diversion, suggesting need for improved diagnostic strategies.
INTRODUCTION: Bariatric surgery is an effective treatment for severe obesity, offering substantial improvements in patients' metabolic profiles. However, increasing attention is being paid to potential long-term complications, including malignancies developing in the excluded portion of the stomach - an area that poses significant diagnostic challenges. CASE REPORT: We report the case of a 68-year-old woman with a history of biliopancreatic diversion, who was diagnosed with advanced diffuse gastric carcinoma 10 years after surgery. The clinical presentation was non-specific, and both laboratory and imaging studies repeatedly yielded false-negative results. A definitive diagnosis was established only during diagnostic laparoscopy - unfortunately, at a stage too advanced for curative treatment. CONCLUSION: This case underscores the risk of late-onset malignancy in the excluded stomach following bariatric surgery and highlights the considerable diagnostic difficulties. Early detection requires a high index of clinical suspicion, access to advanced endoscopic techniques, and close multidisciplinary collaboration. The absence of standardized screening protocols further hampers timely diagnosis.
No takes yet. Share an insight, caveat, or question.
Rada et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: