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April 30, 2026Results in OpticsOpen Access

TDLAS-based exhaled methane detection for screening of cerebrovascular diseases

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Authors

JSJiaxin SongZLZhaopeng LiHZHengrui Zhang

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Overview

This analysis demonstrates higher methane levels in patients with cerebrovascular diseases, suggesting exhaled breath can aid early diagnosis.

Key Points

  • The aim is to evaluate the effectiveness of exhaled methane detection for screening cerebrovascular diseases.
  • Developed a TDLAS-based real-time exhaled methane detection system.
  • Analyzed exhaled breath from healthy controls and patients with cerebrovascular diseases.
  • Employed a support vector machine algorithm for classification modeling.
  • Detected parts-per-billion levels of methane in exhaled breath.
  • Found significantly higher methane concentrations in patients compared to healthy controls (p < 0.05).
  • The transient ischemic attack group showed the highest methane concentration.

Cite This Study

Song et al. (2026) studied this question.

synapsesocial.com/papers/69f2a4f18c0f03fd67764120https://doi.org/10.1016/j.rio.2026.101023
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