Letter highlights importance of radiotherapy for high-risk basal cell carcinoma with perineural invasion, suggesting improved outcomes.
In this letter, we evaluated the recurrent morpheaform BCC case presented by Afzal et al., highlighting that perineural invasion and the morpheaform histologic subtype are high-risk features. We emphasized that adjuvant radiotherapy should not be overlooked in high-risk patients with perineural invasion, even in young individuals, despite clear surgical margins. Additionally, we noted that the omission of tumor size reduced the educational value of the case report.
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Türkmen et al. (2026) studied this question.
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