Why the study?
Do transplanted iPS cells or their conditioned media improve cardiac function and mitigate adverse remodeling in a mouse model of diabetic cardiomyopathy?
Do transplanted iPS cells or their conditioned media improve cardiac function and mitigate adverse remodeling in a mouse model of diabetic cardiomyopathy?
Transplanted iPS cells and their conditioned media attenuate adverse cardiac remodeling and improve function in diabetic cardiomyopathy through paracrine and autocrine mechanisms.
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Preclinical support for iPS cells and CM in diabetic cardiomyopathy models; leaves open human translation.
Yan et al. (2013) studied this question.
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