Why the study?
Do tissue Doppler imaging markers of left ventricular diastolic dysfunction correlate with NT-pro-BNP levels and predict in-hospital mortality in mechanically ventilated ICU patients with preserved EF?
Do tissue Doppler imaging markers of left ventricular diastolic dysfunction correlate with NT-pro-BNP levels and predict in-hospital mortality in mechanically ventilated ICU patients with preserved EF?
In mechanically ventilated ICU patients with preserved EF, LV diastolic dysfunction and sepsis determine NT-pro-BNP levels, and combining TDI markers with NT-pro-BNP improves the prediction of in-hospital mortality.
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TDI markers may enhance NT-proBNP-based mortality prediction in ventilated preserved-EF ICU patients; leaves open prospective validation.
Ikonomidis et al. (2010) studied this question.
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