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Develop a structural continuum framework and hyperelastic free-energy function that accounts for dispersed collagen fiber orientations across arterial layers.

September 28, 2005Journal of The Royal Society InterfaceOpen Access

Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

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Develop a structural continuum framework and hyperelastic free-energy function that accounts for dispersed collagen fiber orientations across arterial layers.
Formulated a generalized hyperelastic free-energy function incorporating a scalar structural parameter to characterize fiber dispersion.
Implemented the constitutive relation into a finite element framework using morphology and light microscopy data from human iliac arteries.
Successfully accounted for the anisotropic elastic stress-strain behavior of adventitial and intimal layers that aligned-fiber models fail to represent accurately.
Showed through numerical simulations that collagen fiber dispersion within the adventitia of human iliac arteries significantly alters tissue mechanical response.

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Implication

Computational modeling study demonstrates significant effects of dispersed collagen fiber orientations in human iliac arterial layers, highlighting improved structural continuum models.

Cite This Study

Gasser et al. (2005) studied this question.

synapsesocial.com/papers/69f2d250b314c0098dde9444 https://doi.org/10.1098/rsif.2005.0073

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Implication

Computational modeling study demonstrates significant effects of dispersed collagen fiber orientations in human iliac arterial layers, highlighting improved structural continuum models.

Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

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Implication

Cite This Study

Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

Key Points

Discussion

Implication

Cite This Study

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