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Rapidly quantifies ginsenosides in Panacis Quinquefolii Radix, highlighting quality differences based on origins.
A rapid, sensitive and reliable method based on ultra performance liquid chromatography coupled with a photodiode array detector (UPLC-PAD) was developed for both the quantitative analysis of ten bioactive ginsenosides and a chemical-fingerprint analysis. The chromatography was performed on an ACQUITY UPLC™ BEH C18 column using a gradient elution with acetonitrile/water as the mobile phase. To compare the UPLC fingerprints and to evaluate their quality, chemometric methods including similarity analysis (SA) and hierarchical-clustering analysis (HCA) were implemented when classifying the Panacis Quinquefolii Radix samples. The Panacis Quinquefolii Radix samples were successfully grouped in accordance with their geographic origins.
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ZHANGa et al. (2011) studied this question.
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