Randomized trial examines periodontal disease severity in psoriasis and psoriatic arthritis, suggesting oral health as a marker for inflammation.
Key Points
This study aims to evaluate the prevalence and severity of periodontitis in patients with psoriasis and psoriatic arthritis and its correlation with disease activity.
Prospective triple-arm case-control study with 120 participants divided into three groups: healthy controls, psoriasis, and psoriatic arthritis.
Detailed periodontal examination including measurement of oral hygiene index, gingival bleeding, probing depth, clinical attachment loss, and missing teeth.
Disease activity measured using PASI for psoriasis, DAS28, and DAPSA for psoriatic arthritis with statistical analysis conducted using Kruskal Wallis and Spearman’s correlation.
Periodontitis prevalence was 89.7% in PsA and 87.8% in psoriasis groups versus 32.5% in healthy controls (p < 0.001).
Severe periodontal disease activity was noted in PsA with significant OHI, bleeding scores, probing depth, and CAL (p < 0.05).
Positive correlations were observed between PASI, DAPSA, DAS28 indices and periodontal disease metrics with statistical significance (p < 0.001).