Case report demonstrates the challenges in diagnosing pemphigus vegetans in patients with lymphoma, suggesting a deeper link between the two conditions.
Key Points
To explore the clinical connection between pemphigus vegetans and diffuse large B-cell lymphoma in a patient with concurrent diagnoses.
Patient with atypical pemphigus vegetans presenting with verrucous lesions and an exophytic lesion.
Diagnosis confirmed through clinical features, histopathology, and serologic evidence against desmoglein 1 and 3.
Unified treatment approach with R-CHOP regimen targeting both conditions.
Patient showed lesion clearance after treatment with R-CHOP, indicating a positive response to lymphoma-targeted therapy.
The timing of pemphigus vegetans eruption correlated with diffuse large B-cell lymphoma recurrence, suggesting a potential association.
This case highlights the need for consideration of rare pemphigus variants as indicators of hematological malignancies.