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April 30, 2026AnimalsOpen Access

Associations Between Gut Microbiota and Fecal Semiochemical and Metabolic Profiles in Sows During the Periparturient Period

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Authors

YWYuansheng WuSouth China Agricultural UniversityHYHaoran YanSouth China Agricultural UniversityCGChuchen GuiSouth China Agricultural University

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Implication

Randomized trial explores associations between gut microbiota and fecal metabolic profiles in sows, suggesting implications for piglet health.

Key Points

  • This research aims to investigate the connections between gut microbiota and fecal semiochemical profiles in sows during the periparturient period.
  • Collected fecal samples from six crossbred sows at 4 days prepartum and 3 days postpartum.
  • Analyzed nutritional components, volatile organic compounds, and gut microbiota using untargeted metabolomics.
  • Assessed changes in microbial diversity and metabolites during the transition from prepartum to postpartum.
  • Postpartum showed an increase in skatole and p-cresol concentrations, with a decrease in microbial alpha diversity.
  • Identified 298 differentially abundant metabolites, with notable changes in nicotinamide metabolism and butyrate production.
  • Spearman correlations revealed skatole and p-cresol were negatively correlated with butyrate-producing bacteria.

Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69f2f1dc1e5f7920c638788dhttps://doi.org/10.3390/ani16091346
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