Comprehensive Analysis of the Beta-Myosin Heavy Chain Gene in 389 Unrelated Patients With Hypertrophic Cardiomyopathy

Driest et al. (Sun,) conducted a observational in Hypertrophic cardiomyopathy (n=389). MYH7 mutations vs. No MYH7 mutations was evaluated on Age at diagnosis (years) (p=0.0002). HCM patients with MYH7 mutations were diagnosed at a younger age (32.9 vs. 42.7 years, p=0.0002) and had more hypertrophy, but no greater frequency of sudden death among first-degree relatives.

www.synapsesocial.com/papers/69f31e80b24eb58ef2fb05ac — DOI: https://doi.org/10.1016/j.jacc.2004.04.039