Why the study?
Atherosclerosis is a chronic inflammatory disease, but data on arterial inflammation at early stages is limited.
Does hybrid PET/MRI detect vascular inflammation in middle-aged individuals with known subclinical atherosclerosis?
Does hybrid PET/MRI detect vascular inflammation in middle-aged individuals with known subclinical atherosclerosis?
Hybrid PET/MRI demonstrates that arterial inflammation is highly prevalent in middle-aged individuals with known subclinical atherosclerosis.
Should not yet change clinical practice in atherosclerosis prevention; leaves open the role of early arterial inflammation as a treatment target.
BACKGROUND: Atherosclerosis is a chronic inflammatory disease, but data on arterial inflammation at early stages is limited. RESULTS: Arterial inflammation was present in 48.2% of individuals (24.4% femorals, 19.3% aorta, 15.8% carotids, and 9.3% iliacs) and plaques in 90.1% (73.9% femorals, 55.8% iliacs, and 53.1% carotids). CONCLUSIONS: Arterial inflammation is highly prevalent in middle-aged individuals with known subclinical atherosclerosis. Large-scale multiterritorial PET/MRI allows characterization of atherosclerosis-related arterial inflammation and demonstrates
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Fernández‐Friera et al. (2019) studied this question.
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