Why the study?
Does volume loading slow left ventricular isovolumic relaxation rate in the intact dog heart?
Does volume loading slow left ventricular isovolumic relaxation rate in the intact dog heart?
This preclinical study demonstrates that volume loading slows left ventricular isovolumic relaxation rate in the intact dog heart.
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Warrants caution interpreting relaxation indices with volume changes; leaves open human translation.
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Raff et al. (1981) studied this question.
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