June 7, 2005Circulation
Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction
Why the study?
Is admission glucose level associated with increased mortality in elderly patients hospitalized with acute myocardial infarction?
Population
141,680 elderly patients hospitalized with acute myocardial infarction from 1994 to 1996 (national sample).
Comparison
Higher admission glucose levels vs Admission glucose ≤110 mg/dL
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Overview
Admission hyperglycemia may flag higher short-term risk in elderly AMI patients without diabetes; leaves open whether targeted control improves outcomes.
Structured PICO
Is admission glucose level associated with increased mortality in elderly patients hospitalized with acute myocardial infarction?
P
Population
141,680 elderly patients hospitalized with acute myocardial infarction from 1994 to 1996 (national sample).
I
Intervention
Higher admission glucose levels (analyzed as categorical: >110 to 140, >140 to 170, >170 to 240, >240 mg/dL, and continuous)
C
Comparator
Admission glucose ≤110 mg/dL
O
Outcome
30-day mortalityhard clinical
Elevated admission glucose is common, often untreated, and strongly associated with increased short- and long-term mortality in elderly AMI patients, especially those without recognized diabetes.
Cite This Study
Kosiborod et al. (2005) studied this question.