Population
Platelets (in vitro model)
Comparison
Immobilized octapeptide KOGEOGPK from type III… vs Type III collagen (for phosphorylation comparison)
Design
Preclinical
Authors
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Indicates a novel GP Ia/IIa- and VI-independent platelet-collagen pathway; leaves open receptor identification and human thrombotic relevance.
The type III collagen-related KOGEOGPK octapeptide mediates platelet adhesion and signaling through a mechanism distinct from GP Ia/IIa and GP VI.
Maurice et al. (2004) studied this question.
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