Why the study?
Does percutaneous coronary intervention using provisional stenting compared to surgical revascularization improve long-term outcomes in patients with left main coronary artery stenosis and cardiorenal-metabolic syndrome?
Does percutaneous coronary intervention using provisional stenting compared to surgical revascularization improve long-term outcomes in patients with left main coronary artery stenosis and cardiorenal-metabolic syndrome?
In patients with significant LMCA stenosis, the presence of cardiorenal-metabolic syndrome worsens prognosis after PCI, suggesting CABG may be the preferred revascularization strategy in this subgroup.
May support preferring CABG in left main stenosis with cardiorenal-metabolic syndrome; leaves open confirmation in randomized trials.
The article presents the results of a prospective study involving 178 patients with coronary artery disease and significant left main coronary artery (LMCA) stenosis. Long-term outcomes after percutaneous coronary intervention (PCI) using the provisional stenting technique were compared with surgical revascularization, in patients with and without cardiorenal-metabolic syndrome (CRMS). It was found that CRMS significantly worsens the prognosis after PCI, while coronary artery bypass grafting neutralizes this negative impact. The findings emphasize the importance of assessing CRMS status when selecting a revascularization strategy in patients with LMCA lesions.
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G. B. Mankovsky (2025) studied this question.
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