Why the study?
Vaccination against COVID-19 provides clear public health benefits, but the risks and outcomes of myocarditis after vaccination were unclear.
Does vaccination with mRNA-based COVID-19 vaccines increase the risk of myocarditis in individuals older than 12 years of age?
Population
192 405 448 individuals older than 12 years receiving mRNA COVID-19 vaccines in the US
Comparison
Observed post-vaccination myocarditis reporting rates vs expected rates from 2017-2019 claims data
Design
Descriptive passive surveillance study using VAERS reports
Authors
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Confirms elevated myocarditis rates after second BNT162b2 dose in males 16-17 years; observational data leaves practice implications open.
Does vaccination with mRNA-based COVID-19 vaccines increase the risk of myocarditis in individuals older than 12 years of age?
Passive surveillance data indicates an increased risk of myocarditis following mRNA-based COVID-19 vaccination, particularly among adolescent males and young men after the second dose.
Oster et al. (2022) studied this question.
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