Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 2026SHILAP Revista de lepidopterologíaOpen Access

Enhanced secretion of extracellular proteins in Trichoderma reesei through targeted deletion of a kinesin encoding gene

View Full Paper
Ask AI
Bookmark
Share

Authors

HCHuizhen ChenFujian Normal UniversityYZYuqiang ZhengFujian Normal UniversityHSHaowen SunFujian Normal University

Discussion

Loading...

Member takes

Overview

Randomized trial shows improved cellulase production in Trichoderma reesei through targeted gene deletion, suggesting a novel genetic strategy.

Key Points

  • The aim is to evaluate how deleting the kinesin gene kin1 affects protein secretion and cellulase production in Trichoderma reesei.
  • Targeted deletion of kinesin gene kin1 in Trichoderma reesei.
  • Assessment of morphological changes, biomass increase, and cellulase activity.
  • Transcriptome analysis to evaluate gene expression levels.
  • The Δkin1 strain exhibited increased cellulase production, with higher titers and activities during fermentation.
  • Alterations in hyphal morphology included shorter, branched hyphae and improved biomass.
  • Gene expression of major cellulase genes remained largely unchanged despite enhanced enzyme production.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69f44223967e944ac5565dbahttps://doi.org/10.1080/21501203.2026.2659416
View Full Paper
Ask AI
Bookmark
Share