Dear Editor,We read with great interest the article entitled “Prediction of Total Bilirubin Levels in Newborns Using Machine Learning”. Machine learning -based approaches for the early identification of neonatal hyperbilirubinemia represent an important and evolving field within clinical decision support systems.In the study, multiple ML algorithms were compared, and the Gradient Boosting model demonstrated the highest accuracy and AUC values in the test dataset . However, the dataset exhibited a marked class imbalance (
Coşkun et al. (Tue,) studied this question.