BACKGROUND: methylation is a well-established biomarker of epigenetic age, yet its dynamics following lung cancer resection have not been characterized. RESULTS: < 0.0001). The reduction in methylation was more pronounced in female patients, whereas classification accuracy was lower in older individuals. SIGNIFICANCE: methylation-a marker of epigenetic aging-in early-stage lung cancer patients. This observation warrants further investigation.
Li et al. (Tue,) studied this question.