Systematic review finds probiotic interventions may lower hemoglobin A1c and insulin requirements in children with type 1 diabetes, suggesting potential therapeutic benefits.
= 0%). Subgroup analysis revealed that the De Simone formulation explained 70.32% of the between‑study variance. No publication bias was detected.ConclusionProbiotic supplementation, particularly specific formulations, may reduce glycated hemoglobin levels and insulin needs in children with type 1 diabetes, supporting probiotics supplementation as an adjunctive therapy; however, larger trials are needed to confirm these findings.
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Su et al. (2026) studied this question.
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