Key result
Elective LAD stenting linked to apical Takotsubo syndrome mimicking acute MI without thrombosis.
Why the study?
Takotsubo syndrome after percutaneous coronary intervention is rare and may be misinterpreted as a procedural complication, including type 4a myocardial infarction.
Case Report (n=1)
Takotsubo syndrome can occur after elective PCI and should be differentiated from periprocedural MI using cardiac MRI to avoid unnecessary escalation of antithrombotic therapy.
Clinicians should differentiate post-PCI TS from type 4a MI; leaves open incidence after elective stenting and need for prospective studies.
BACKGROUND: Takotsubo syndrome (TS) is a transient stress-induced left ventricular dysfunction that may clinically mimic acute myocardial infarction (MI). Its occurrence after percutaneous coronary intervention is rare, and it may be misinterpreted as a procedural complication, including type 4a MI. CASE SUMMARY: We describe a 77-year-old woman with stable coronary artery disease who developed apical TS shortly after elective stenting of the left anterior descending artery. Postprocedural chest pain and electrocardiographic changes raised suspicion of acute MI. However, coronary angiography demonstrated patent stent implantation without evidence of acute thrombosis. Cardiac magnetic resonance imaging confirmed apical ballooning with myocardial edema in the absence of necrosis, consistent with TS. DISCUSSION: TS after percutaneous coronary intervention is an uncommon but important diagnostic consideration. Differentiation from periprocedural MI requires integration of clinical findings, coronary imaging, and cardiac magnetic resonance imaging. Recognition of this condition is essential to avoid unnecessary escalation of antithrombotic therapy and to guide appropriate management.
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Vitalieva et al. (2026) conducted a case report in Takotsubo syndrome (n=1). Elective stenting of the left anterior descending artery was evaluated. Elective stenting of the left anterior descending artery in a 77-year-old woman was followed by apical Takotsubo syndrome, mimicking acute myocardial infarction without acute thrombosis.
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