Pd₁Aul/Graphene: Highly Efficient Bimetallic Single-Atom Catalysts for C-C Coupling from C-B Bond Activation.

/graphene, where adjacent Pd and Au atoms form a synergistic active center. This promotes simultaneous aromatic boronic acid substrate activation and significantly reduces the reaction energy barrier of the oxidative addition step, thereby enabling a pathway inaccessible to isolated single atoms. This work not only provides an efficient catalyst for organic synthesis but also validates the fundamental principle of synergistic catalysis in bimetallic single-atom catalysts, offering a universal design strategy for addressing challenging transformations.