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May 1, 2026Journal of Clinical MedicineOpen Access

Doppler–Scintigraphy Combination with Thyroxine Profiling Enhances Diagnostic Accuracy of Thyroid Lesions: A 144-Patient Cross-Sectional Study

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Authors

RTReham Mohamed TahaMGMoawia GameraddinYEYasir Hassan Elhassan

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Overview

Cross-sectional study shows multimodal imaging improves diagnostic accuracy of thyroid lesions, indicating better outcomes for patients.

Key Points

  • Assessing the effectiveness of Doppler ultrasound, nuclear scintigraphy, and thyroxine levels in diagnosing thyroid diseases.
  • 144 patients analyzed with a multimodal imaging approach
  • Utilized fine-needle aspiration cytology results for diagnosis
  • Conducted multivariate logistic regression to identify predictors of malignancy.
  • Combined model achieved 79.6% sensitivity and 68.2% specificity for malignancy detection
  • Increased Doppler vascularity was an independent predictor of malignancy (OR = 2.39)
  • High T4 levels and scintigraphic uptake were not significant predictors.

Cite This Study

Taha et al. (2026) studied this question.

synapsesocial.com/papers/69f44488967e944ac5567802https://doi.org/10.3390/jcm15093364
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