Investigating the potential of Ulva rigida extracts as a natural anti-aging agent in cosmetics.

of 1.38 ± 0.68 mg/ml), and also promoted collagen biosynthesis (37.68 ± 2.24%). All UR extract was particularly notable for its ability to stimulate key anti-aging gene, SIRT1, which is superior to resveratrol (87.8 ± 1.8%). Importantly, none of the extracts showed cytotoxicity at a concentration of 1.0 mg/mL, confirming their safety for use on human skin. These findings suggest that the sea lettuce (UR) extracts are a strong candidate for future development as an anti-aging agent in the cosmetic industry.