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May 1, 2026

Comparison of dynamic contrast-enhanced MRI versus MAG-3 scintigraphy for differential renal function assessment in pediatric patients.

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Authors

CACemre AriyurekLTLiam TimmsBoston Children's HospitalXCXinhua CaoBoston Children's Hospital

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Implication

Retrospective study evaluates renal function assessment in children using DCE-MRI and MAG-3 scintigraphy, suggesting strong agreement between methods.

Key Points

  • To evaluate the agreement between differential renal function values derived from DCE-MRI and MAG-3 scintigraphy in pediatric patients.
  • Retrospective analysis of 23 pediatric patients aged 3 months to 20 years with both DCE-MRI and MAG-3 scintigraphy performed within 6 months.
  • DCE-MRI used a golden-angle radial dynamic acquisition with two-compartment tracer kinetic model for analysis.
  • Agreement assessed using Bland-Altman analysis, Pearson, and concordance correlations.
  • Mean DRF difference with default MAG-3 was 0.4% (95% CI, -3.3% to 4.2%); 78.3% of cases fell within ±10%.
  • Concordance correlation coefficient was 0.870 (95% CI, 0.718-0.942).
  • No significant bias found; C-shaped background correction showed a mean difference of -2.3% with CCC of 0.845 (95% CI, 0.614-0.943).

Cite This Study

Ariyurek et al. (2026) studied this question.

synapsesocial.com/papers/69f444d3967e944ac55678echttps://doi.org/10.1007/s00247-026-06624-z
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