Why the study?
Data on ventricular fibrotic processes in the pathogenesis of AF and its complications are controversial, and the mutual effect of fibrosis in coexisting AF and heart failure requires better understanding.
Design
Review paper
Authors
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Ventricular fibrosis role in AF warrants clinical caution; leaves open its contribution to diastolic dysfunction pending dedicated trials.
This review provides an overview of the mechanisms, differences, and clinical significance of atrial and ventricular fibrosis in patients with atrial fibrillation.
Dzeshka et al. (2015) studied this question.
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