Why the study?
Is amiodarone appropriate for rhythm control in a patient with recurrent, symptomatic atrial fibrillation and multiple comorbidities?
Is amiodarone appropriate for rhythm control in a patient with recurrent, symptomatic atrial fibrillation and multiple comorbidities?
Amiodarone is an effective antiarrhythmic for rhythm control in atrial fibrillation, but its use requires careful consideration of potentially serious toxic effects.
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Requires toxicity vigilance with amiodarone for AF rhythm control; leaves open optimal selection in comorbid patients.
A 73-year-old man with coronary artery disease, hypertension, and renal insufficiency presents with recurrent, symptomatic atrial fibrillation despite a well-controlled ventricular rate. Amiodarone is recommended for rhythm control. Amiodarone is among the most effective antiarrhythmic agents, but its use is associated with potentially serious toxic effects — is it right for this patient?
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Peter Zimetbaum (2007) studied this question.
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