September 22, 2017SHILAP Revista de lepidopterología211 citationsOpen Access

Sex Differences in the Utilization and Outcomes of Surgical Aortic Valve Replacement for Severe Aortic Stenosis

ZCZakeih ChakerWest Virginia University VBVinay BadhwarCardiac Surgery FAFahad AlqahtaniWest Virginia University

Structured PICO

Does female sex worsen in-hospital mortality following surgical aortic valve replacement for severe aortic stenosis compared to male sex?

Population

Patients undergoing surgical aortic valve replacement (AVR) for severe aortic stenosis from the Nationwide Inpatient Sample

Intervention

Female sex

Comparator

Male sex

Outcome

In-hospital mortalityhard clinical

Women experience worse in-hospital mortality following surgical aortic valve replacement compared to men, suggesting transcatheter AVR might be preferable for women.

Abstract

BACKGROUND: Studies assessing the differential impact of sex on outcomes of aortic valve replacement (AVR) yielded conflicting results. We sought to investigate sex-related differences in AVR utilization, patient risk profile, and in-hospital outcomes using the Nationwide Inpatient Sample. METHODS AND RESULTS: <0.001). CONCLUSIONS: Women have worse in-hospital mortality following AVR compared with men. Coupled with the accumulating evidence suggesting higher magnitude of benefit of transcatheter AVR over AVR in women, women should perhaps be offered transcatheter AVR over AVR at a lower threshold than men.

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