Why the study?
Do sensitive cardiac troponin assays improve the diagnostic accuracy for acute myocardial infarction compared to a standard assay in patients presenting to the emergency department with suggestive symptoms?
Population
718 consecutive patients presenting to the emergency department with symptoms suggestive of acute myocardial…
Comparison
Four sensitive cardiac troponin assays performed… vs Standard cardiac troponin assay.
Design
Cohort, blinded fashion
Authors
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May support sensitive troponin assays for earlier ED AMI diagnosis; extends observational data but leaves randomized validation open.
Do sensitive cardiac troponin assays improve the diagnostic accuracy for acute myocardial infarction compared to a standard assay in patients presenting to the emergency department with suggestive symptoms?
Sensitive cardiac troponin assays provide excellent diagnostic performance and substantially improve the early diagnosis of acute myocardial infarction compared to standard assays, especially in patients presenting within 3 hours of symptom onset.
Reichlin et al. (2009) studied this question.
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