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Preclinical study demonstrates negligible toxicity of a novel ionic liquid carrier, indicating potential for transdermal chemotherapy delivery.
skin irritation tests revealed that the new carrier had a negligible toxicity profile compared with a conventional ionic liquid-based carrier. Based on these findings, we believe that the SAIL[Cho][Ole]-based MF has potential as a biocompatible nanocarrier for the effective transdermal delivery of poorly soluble chemotherapeutics such as PTX.
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Ali et al. (2021) studied this question.
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