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Case report reveals a rare occurrence of EBV-positive follicular dendritic cell sarcoma in the testes, indicating diagnostic challenges.
Follicular dendritic cell sarcoma (FDCS) is an exceedingly rare low-grade malignant tumor originating from follicular dendritic cells. It is classified into two subtypes: the classic type and the EBV-positive inflammatory follicular dendritic cell sarcoma (EBV+ iFDCS). While EBV+ iFDCS predominantly arises in abdominal organs such as the liver and spleen, its morphological spectrum is broad, rendering diagnosis challenging. Here, we report an exceptionally rare case of EBV+ iFDCS occurring in the testes, a site previously unreported in the literature.
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Meng et al. (2026) studied this question.
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