Antiangiogenic therapy after cataract surgery in neovascular age-related macular degeneration (clinical observation)

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This research evaluates the safety and impact of cataract surgery on neovascular age-related macular degeneration (nAMD) progression.
Patients underwent phacoemulsification with intraocular lens implantation and were treated with aflibercept or brolucizumab.
Assessment included BCVA, central retinal thickness, and imaging evaluations over 12 months pre- and post-surgery.
Statistical analysis focused on changes in visual acuity and CRT.
BCVA improved by 0.10 in the brolucizumab group and 0.05 in the aflibercept group.
CRT decreased by 46 µm for brolucizumab and 29 µm for aflibercept.
Brolucizumab patients showed significant improvement in reducing subretinal and intraretinal fluid occurrences.

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Assesses nAMD progression post-cataract surgery, suggesting safe anti-VEGF continuity.

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Litvina et al. (2026) studied this question.

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