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May 2, 20260 citations

Psychosocial interventions for mental health difficulties following moderate-to-severe traumatic brain injury: A systematic review and meta-analysis.

SCSarah CarrierLa Trobe University DWDana WongLa Trobe University HEHolly EmeryUniversity of Tasmania

Key Points

To evaluate the effectiveness of psychosocial interventions for mental health difficulties following moderate-to-severe traumatic brain injury.
Systematic review and meta-analysis of studies on psychosocial interventions post-TBI.
Assessment of various mental health outcomes including anxiety, depression, and substance misuse.
Evaluation of evidence quality using GRADE methodology.
Psychosocial interventions, particularly cognitive behavioral therapy (CBT), show potential benefits for mental health post-TBI.
GRADE certainty of evidence was low for anxiety, depression, and distress outcomes.
Very low certainty for alcohol misuse, insomnia, and sexual dysfunction outcomes.

Abstract

= 0.30). GRADE certainty of evidence was low for anxiety, depression, distress and suicidality, and very low for alcohol/substance misuse, sleep difficulties/insomnia and sexual dysfunction. Psychosocial interventions appear beneficial for mental health difficulties post-TBI, with most consistent evidence for CBT. Findings will inform Clinical Practice Guidelines.

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