Mechanistic analysis reveals bromophenols effectively scavenge radicals in polar environments, suggesting antioxidant potential.
, while activity significantly decreased in nonpolar media. Mechanistic analysis indicates that, under polar conditions, the sequential proton loss-electron transfer (SPLET) pathway predominates, whereas electron transfer mechanisms are disfavored in non polar environments. Overall, BPs are effective radical scavengers, particularly in polar media, highlighting their potential as simple antioxidant motifs.
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Boulebd et al. (2026) studied this question.
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