PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
May 2, 2026

Efficacy and safety of combining microneedling with oral doxycycline for the treatment of rosacea: a retrospective comparative cohort study.

View Full Paper
Ask AI
Bookmark
Share

Authors

KXKuanyu XiaYPYiran PengZJZixi Jiang

Discussion

Loading...

Member takes

Overview

Retrospective cohort study shows improved outcomes in rosacea with microneedling plus doxycycline, suggesting enhanced efficacy.

Key Points

  • This study aims to determine if microneedling enhances the effect of oral doxycycline in treating rosacea symptoms.
  • Retrospective comparative cohort study with 80 participants.
  • Evaluated treatment success rate for facial erythema at week 12.
  • Assessed secondary outcomes including inflammatory lesions and safety.
  • Adding microneedling led to significantly greater improvement in facial erythema and burning sensations (p<0.001).
  • The combination therapy also reduced erythema relapse at 6 months.
  • No severe adverse events were reported.

Cite This Study

Xia et al. (2026) studied this question.

synapsesocial.com/papers/69f5945c71405d493afff261https://doi.org/10.1080/09546634.2026.2665538
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of the Efficacy of Intense Pulsed Light Combined with Doxycycline in the Treatment of Rosacea2024
  2. 2Clinical Outcomes and Predictive Factors of Combination Treatment With Oral Doxycycline, Topical Calcineurin Inhibitor, and Pulsed Dye Laser in Erythematotelangiectatic Rosacea2026
  3. 3Efficacy and Safety of Hydroxychloroquine Combined With Doxycycline for the Treatment of Patients With Rosacea: A Randomized, Double‐Blind, Double‐Dummy Clinical Trial2025
  4. 4A comparative exploration of immunohistochemical markers in patients with papulopustular rosacea undergoing treatment with oral isotretinoin versus doxycycline2024 · 3 citations
  5. 5Laser and energy‐based devices for treating rosacea ‐ a systematic review and network meta‐analysis2025