Photobiomodulation therapy in the treatment of genitourinary syndrome in postmenopausal women - a placebo-controlled double-blind clinical trial.

Postmenopausal genitourinary syndrome of menopause (GSM) includes a range of genital, urinary and sexual symptoms caused by estrogen deficiency. As women spend about one-third of their lives postmenopause, effective, non-invasive treatments are needed. This study evaluated the clinical effects of photobiomodulation (PBM) therapy in postmenopausal women with urinary incontinence. A randomized, double-blind, placebo-controlled clinical trial was conducted with women over 50 years of age presenting one or more GSM symptoms. Participants were assigned to receive either PBM or placebo. The PBM group underwent four weekly sessions of 808 nm laser applied to eight vaginal points (4J per point, 40s each). The placebo group followed the same protocol with the device turned off. Results showed a significant reduction in urinary loss in the PBM group, with improved scores on the International Consultation on Incontinence Questionnaire - Short Form. While pelvic pressure and sexual function did not differ significantly, improvements in vaginal dryness and burning were reported. PBM appears to be a promising, non-invasive option for reducing urinary incontinence and enhancing aspects of vaginal health in postmenopausal women. Further studies are needed to confirm long-term effects and optimize treatment protocols.