What question did this study set out to answer?

The aim is to identify patient-level factors contributing to high healthcare costs in individuals experiencing first-episode psychosis.

May 2, 2026

Factors associated with high-cost patients with first-episode psychosis: a retrospective study of direct healthcare costs using US private-payer claims data.

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Retrospective study characterizes factors influencing high healthcare costs in first-episode psychosis patients, indicating intervention needs.

The aim is to identify patient-level factors contributing to high healthcare costs in individuals experiencing first-episode psychosis.
Analyzed commercial insurance claims data from 2013 to 2019 for FEP patients
Classified patients as high-cost (HC) or non-high-cost (NHC) based on direct healthcare expenditures
Utilized binomial logistic regression to identify factors associated with HC.
12% of 27,587 FEP patients were classified as high-cost (HC)
HC patients had significantly higher rates of multiple psychotic disorders (p<0.001) and chronic medical conditions (p<0.001)
Healthcare cost analysis indicated increased inpatient use in HC for both psychosis and non-psychosis-related conditions.

Sridhar et al. (2026) studied this question.

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Retrospective study characterizes factors influencing high healthcare costs in first-episode psychosis patients, indicating intervention needs.