What question did this study set out to answer?

The aim is to explore the protective effects of phenolic compounds from Acer tegmentosum against Toxoplasma-induced liver injury.

Protective Effects of the Hepatoprotective Phenolic Compounds From Acer Tegmentosum Maxim on Toxoplasma‐Induced Acute Liver Injury in Mice

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Randomized trial demonstrates protective effects against Toxoplasma-induced liver injury in mice, suggesting new treatments.

The aim is to explore the protective effects of phenolic compounds from Acer tegmentosum against Toxoplasma-induced liver injury.
Four phenolic compounds were isolated from Acer tegmentosum stem bark and identified via NMR.
Liver and spleen indices, serum ALT, AST, GSH, and MDA levels were measured to evaluate hepatoprotective effects.
Molecular docking analyzed binding interactions between phenolic compounds and T. gondii calcium-dependent protein kinase 1.
Gallic acid showed the strongest anti-T. gondii activity (*p < 0.001).
Acer tegmentosum extract significantly reduced serum levels of ALT, AST, and MDA (*p < 0.05).
Molecular docking indicated strong binding of compounds to TgCDPK1 with energies between -6.1 to -7.6 kcal/mol.

Yin et al. (2026) studied this question.

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