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Assesses torque teno virus and immunosuppression in lung transplantation recipients, suggesting good tolerance at high altitudes.
copies/mL lower in the MSD than in the EDTA plasma. The tacrolimus and everolimus trough levels remained stable during the expedition (p = 0.326 and 0.894, respectively). Eleven LuTx recipients reached the summit without any adverse events, proving extreme physical exertion, even at high altitudes, safe for selected patients. The stable immunosuppressive drug trough levels and TTV loads indicate good tolerance relative to physical stress. MSDs represent a valuable tool for monitoring TTV and immunosuppressive drug trough levels in remote or resource-limited settings.
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Mühlbacher et al. (2026) studied this question.
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